Dali Han

Personal experience: 
2003- 2007: B.S, University of Science and Technology of China
2007- 2012: Ph.D, in Bioinformatics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
2012- 2017: postdoctoral scholar at the University of Chicago
2017-present: Beijing Institute of Genomics, Chinese Academy of Sciences, Principal Investigator

Research Interests:
DNA and RNA epigenetics
Tumor Immunology Genomics
Bioinformatics

​Email:handl(at)big.ac.cn

Dr. Jianhui Zhu

Email：zhujh(at)big.ac.cn
​Publications：
1. Siyuan Su, Xu Zhu, Liang Lin, Xianwei Chen, Yang Wang, Jin Zi, Yusheng Dong, Yingying Xie, Yinghui Zhu, Ju Zhang, Jianhui Zhu, Dan Xu, Ningzhi Xu, Xiaomin Lou*, Siqi Liu*, Lowering endogenous cathepsin D abundance results in reactive oxygen species accumulation and cell senescence, Molecular & Cellular Proteomics, 2017, 16(7):1217-1232.
2. Jianhui Zhu, Huijie Liu, Jia Zhang, Pan Wang, Siqi Liu, Guozhen Liu and Lin Wu*, Effects of Asn-33 glycosylation on the thermostability of Thermomyces lanuginosus lipase, Journal of Applied Microbiology, 2014, 117(1): 151-159
3. Shuang Liu, Jianhui Zhu, Liping He, Jun Dai, Huibin Lu*, Lin Wu*, Kuijuan Jin, Guozhen Yang, and Heng Zhu*, Label-free, real-time detection of the dynamic processes of protein degradation using oblique-incidence reflectivity difference method, Applied Physics Letters, 2014, 104(16): 163701.
4. Yinghao Cao, Jian Sun, Jianhui Zhu, Liyun Li, Guozhen Liu*, PrimerCE: designing primers for cloning and gene expression, Molecular Biotechnology, 2010, 46(2): 113-117
5. Qifeng Song#, Guozhen Liu#, Shaohui Hu, Yan Zhang, Yong Tao, Yuning Han, Haipan Zeng, Wei Huang, Fang Li, Peng Chen, Jianhui Zhu, Chaojun Hu, Shulan Zhang, Yongzhe Li*, Heng Zhu*, Lin Wu*, Novel autoimmune hepatitis-specific autoantigens identified using protein microarray technology, Journal of Proteome Research, 2010, 9(1):30-39.

Dr. Jie Li

Email：lijie(at)big.ac.cn
Personal experience:
2007.9- 2011.6  Bachelor of pharmacy, school of pharmacy, Hebei Medical University.
2011.9- 2016.6  Doctor of chemical biology, school of pharmacy, Nankai University.
2016.11- 2018.12 Postdoctoral scholar, State Key Laboratory of Medicinal Chemical Biology, Nankai University.
2019.3- present  Research assistant，Beijing Institute of Genomics, Chinese Academy of Sciences.

Publications：
1.Li, J.; Bai, T. R.; Gao, S.; Zhou, Z.; Peng, X. M.; Zhang, L. S.; Dou, D. L.; Zhang, Z. S.; Li, L. Y., Human rhomboid family-1 modulates clathrin coated vesicle-dependent pro-transforming growth factor alpha membrane trafficking to promote breast cancer progression. EBioMedicine, 2018, 36, 229-240.
2.Li, J.; Liu, X.; Gao, Y.; Zong, G.; Wang, D.; Liu, M.; Fei, S.; Wei, Y.; Yin, Z.; Chen, J.; Wang, X.; Shen, Y., Identification of a UDP-Glucosyltransferase favouring substrate- and regio-specific biosynthesis of flavonoid glucosides in Cyclocarya paliurus. Phytochemistry, 2019, 163(C), 75-88.
3.Zong, G.; Fei, S.; Liu, X.; Li, J.; Gao, Y.; Yang, X.; Wang, X.; Shen, Y., Crystal structures of rhamnosyltransferase UGT89C1 from Arabidopsis thaliana reveal the molecular basis of sugar donor specificity for UDP-beta-l-rhamnose and rhamnosylation mechanism. Plant J., 2019. doi:10.1111/tpj.14321
4.Zong, G.; Li, J.; Gao, Y.; Fei, S.; Liu, X.; Wang, X.; Shen, Y., Overexpression, purification, biochemical and structural characterization of rhamnosyltransferase UGT89C1 from Arabidopsis thaliana. Protein Expr Purif., 2019, 156, 44-49.
5.Qi, J. W.; Qin, T. T.; Xu, L. X.; Zhang, K.; Yang, G. L.; Li, J.; Xiao, H. Y.; Zhang, Z. S.; Li, L. Y., TNFSF15 inhibits vasculogenesis by regulating relative levels of membrane-bound and soluble isoforms of VEGF receptor 1. Proc Natl Acad Sci U S A., 2013, 110 (34), 13863-8.
6.Song Chao, He Jie, Li Jie, Zhao Hongyi, Fu Yan. Research progress on sodium borohydride reduction system of carboxylic acid and its derivatives[J]. Chemistry, 2012, 75(07): 614-620.
7.Song Chao, He Jie, Li Jie, Zhao Hongyi, Fu Yan. Catalytic synthesis of sodium borohydride of cyclohexylmethylamine [J]. Chemical reagents, 2012, 34(06): 555-558.

Patent：

Li Luyuan, Zhang Zhisong, Dou Daolei, Li Jie, Shu Feifei, Zheng Yangyang. Peptides that inhibit the stability of HIF1α and their applications: China, CN 104877030, [P]. 2015-09-02.